5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor widely used in laboratory environments to study nicotinamide N-methyltransferase (NNMT) activity. NNMT is an enzyme involved in cellular methylation pathways and metabolic regulation, making 5-Amino-1MQ a valuable tool in experiments examining energy homeostasis, NAD⁺-related biochemistry, and adipocyte metabolism.
In vitro research demonstrates that inhibiting NNMT can influence nicotinamide adenine dinucleotide (NAD⁺) levels, downstream metabolic signaling, and cellular responses to nutrient stress. This has led to growing scientific interest in using 5-Amino-1MQ to investigate metabolic rate modulation, gene-regulation pathways (such as SIRT1), and NNMT-mediated chemical processes.
All batches are produced under controlled laboratory conditions with third-party purity verification, ensuring consistent performance for experimental systems.
For laboratory research only. Not for human consumption.
Primary Research Areas:
- NNMT inhibition and methylation-cycle regulation
- NAD⁺ synthesis and cellular energy pathways
- Adipocyte metabolic studies
- Gene-expression analysis related to SIRT1 and metabolic signaling
- Diet-induced obesity mechanisms in preclinical models
- Cellular energy homeostasis and biochemical pathway mapping
5-Amino-1MQ Structure:
Molecular Formula: C10H11N2
Molecular Weight: 159.21 g/mol
PubChem ID: 950107
CAS Number: 42464-96-0
Synonyms: 5-amino-1-methylquinolinium, 5amino-1MQ
