GHK-Cu is a copper-binding tripeptide composed of the sequence glycyl-L-histidyl-L-lysine complexed with a copper(II) ion. First identified in plasma and later detected in other biological fluids, this compound is widely used in laboratory settings to study cellular signaling, tissue remodeling, and regenerative pathways.
In controlled experimental models, GHK-Cu is frequently examined for its involvement in collagen-related pathways, antioxidant activity, cellular repair, and gene expression modulation. Research also explores its role in fibroblast behavior, matrix remodeling, and oxidative stress responses, making it a valuable tool for biochemical and molecular biology investigations.
Primary Research Areas:
- Collagen synthesis and extracellular matrix regulation
- Copper-dependent biochemical signaling
- Oxidative stress and antioxidant activity models
- Gene expression and cellular communication studies
- Fibroblast activity and tissue remodeling
- Regenerative biology and wound-healing pathways
- Skin and hair follicle cellular models
GHK-Cu Structure:
Molecular Formula: C14H23CuN6O4
Molecular Weight: 401.91 g/mol
PubChem ID: 73587
CAS Number: 89030-95-5
Synonyms: Copper Tripeptide-1, GHK Copper, Prezatide Copper, Glycyl-L-histidyl-L-lysine Copper Complex
