SS-31 (also known as elamipretide) is a synthetic tetrapeptide engineered to selectively associate with mitochondrial membranes in controlled laboratory environments. Its unique aromatic–cationic structure enables targeted interaction with cardiolipin, a phospholipid located on the inner mitochondrial membrane, making SS-31 a valuable tool for studying mitochondrial stability, oxidative‐stress pathways, and energy-production mechanisms.
In preclinical and in vitro research models, SS-31 is commonly used to investigate electron transport chain activity, reactive oxygen species modulation, and mitochondrial membrane integrity. Because of its high membrane permeability and predictable binding behavior, it is frequently applied in experiments involving mitochondrial dysfunction simulations, bioenergetic profiling, and cellular stress signaling.
Every batch is produced under stringent laboratory standards and undergoes third-party verification to ensure high purity and consistency for research use.
Primary Research Areas:
- Cardiolipin interaction and mitochondrial membrane studies
- Electron transport chain and ATP-generation models
- Cellular oxidative-stress signaling pathways
- Mitochondrial permeability and stability research
- Reactive oxygen species (ROS) modulation
- Bioenergetic profiling in preclinical systems
- Mitochondrial dysfunction modeling
SS-31 Structure:
Molecular Formula: C32H49N9O5
Molecular Weight: 639.8 g/mol
PubChem ID: 11764719
CAS Number: 736992-21-5
Synonyms: Elamipretide, MTP-131, Bendavia
